PATHWAYS ENRICHMENT AND AGE-RELATED PHENOTYPES: NON-PLEIOTROPIC SNPS VERSUS PLEIOTROPIC SNPS
نویسندگان
چکیده
منابع مشابه
Associations between a Polymorphism in the Pleiotropic GCKR and Age-Related Phenotypes: The HALCyon Programme
BACKGROUND The glucokinase regulatory protein encoded by GCKR plays an important role in glucose metabolism and a single nucleotide polymorphism (SNP) rs1260326 (P446L) in the gene has been associated with several age-related biomarkers, including triglycerides, glucose, insulin and apolipoproteins. However, associations between SNPs in the gene and other ageing phenotypes such as cognitive and...
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ژورنال
عنوان ژورنال: Innovation in Aging
سال: 2017
ISSN: 2399-5300
DOI: 10.1093/geroni/igx004.2050